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. 2019 Aug 6;5(2):e001008. doi: 10.1136/rmdopen-2019-001008

Table 2.

Univariate and multivariate linear regression analyses using ASDAS-CRP as dependent variables

Univariate analyses using ASDAS-CRP as dependent variable Multivariate analyses using ASDAS-CRP as dependent variable and ADCmax as independent variable (N=70) Multivariate analyses using ASDAS-CRP as dependent variable and ADCmean as independent variable (N=70)
Standard coefficient Regression coefficient (95% CI) P value Standard coefficient Regression coefficient (95% CI) P value Standard coefficient Regression coefficient (95% CI) P value
HLA-B27 positivity (N=77) −0.19 −0.44 (−0.95 to −0.07) 0.09 −0.21 −0.51 (−1.03 to 0.02) 0.06 −0.21 −0.49 (−1.02 to 0.05) 0.08
Swollen joint count (N=75) 0.19 0.18 (−0.03 to 0.39) 0.10 0.14 0.14 (−0.07 to 0.34) 0.19 0.15 0.14 (−0.06 to 0.35) 0.17
ADCmax (N=78) 0.29 0.001 (0.00 to 0.001) 0.01 0.27 0.001 (0.00 to 0.001) 0.02
ADCmean (N=78) 0.28 0.001 (0.00 to 0.002) 0.01 0.21 0.001 (0.00 to 0.002) 0.07
SPARCC spine MRI score (N=74) 0.31 0.03 (0.01 to 0.04) 0.01 0.32 0.03 (0.01 to 0.05) 0.01 0.34 0.03 (0.01 to 0.05) <0.01
Age (N=78) 0.05 0.003 (−0.01 to 0.02) 0.67
Male gender (N=78) −0.09 −0.15 (−0.55 to 0.25) 0.45
Smoker (N=78) 0.17 0.30 (−0.01 to 0.68) 0.13
Drinker (N=78) 0.12 0.31 (−0.27 to 0.89) 0.30
Duration of back pain (N=77) −0.01 −0.001 (−0.02 to 0.02) 0.94
Family history of SpA (N=75) 0.15 0.30 (−0.16 to 0.77) 0.20
Tender joint count (N=75) 0.16 0.09 (−0.04 to 0.21) 0.18
Ever enthesitis (N=78) 0.10 0.17 (−0.20 to 0.55) 0.37
nADCmax (N=78) 0.01 0.10 (−0.09 to 0.10) 0.91
nADCmean (N=78) 0.04 0.04 (−0.16 to 0.23) 0.73
SPARCC SI MRI score (N=67) 0.13 0.02 (−0.02 to 0.06) 0.30

ADC, apparent diffusion coefficient; ADCmax, maximum apparent diffusion coefficient; ASAS, Assessment of Spondyloarthritis International Society; CRP, C reactive protein; HLA, human leucocyte antigen; N, number; NaDCmax, normalised maximum apparent diffusion coefficient; SI, sacroiliac; SPARCC, Spondyloarthritis Research Consortium of Canada; SpA, spondyloarthritis.