Table 2.

Summary of ovarian cancer exosomal miRNAs involved with metastasis

Exosomal miRNAs	Recipient cells	Role/Mechanism	Reference
miR-940, miR-222-3p,miR-21–3p, miR-125 b-5p, miR-181 d-5p	TAMs	M2 phenotype polarization, EOC proliferation and migration	[39–41]
miRNA 21 and 29a	ES2 OC cellsLP9 mesothelial cells	Mesothelial cell clearance	[42]
miR-99a-5p	HPMC	Cell invasion through fibronectin and vitronectin upregulation	[43]
MMP1 mRNAs	MeT-5A and HPMC	Destruction of peritoneal mesothelium barrier	[44]
let-7a-f and miR-200a-c	N/A	Correlates with ovarian cancer invasiveness	[45]

Abbreviations: TAMs Tumor-associated macrophages, HPMC Human peritoneal mesothelial cells, OC ovarian cancer, EOC Epithelial ovarian cancer, MMP Matrix metallopeptidase