Fig. 13.

Pelnac increases vascular endothelial growth factor (VEGF) expression in rat wound tissue on day 7 post-operation. (Top) VEGF expression following treatment with Pelnac or Vaseline gauze as an overlay on day 7, as determined by immunohistochemistry (× 200). Scale bars, 250 μm. (Middle and bottom) VEGF expression following treatment with Pelnac or Vaseline gauze as determined by western blotting and quantitative analysis of expression levels. The level in normal skin was set to 1. Data are presented as mean ± standard devistion. Error bars indicate standard deviation. Statistical analysis was performed by Student's t-test.*p < 0.05, **p < 0.01