Figure 3.

Aurigene compounds (1–3) show no inhibition between 300 nM and 300 μM for PD-L1 flowing over PD-1. Soluble PD-L1 was flowed across surface-bound PD-1 with and without test compounds at varying concentrations. The response is normalized to the control protein interaction (PD-L1 only). Responses were measured in triplicate, and error bars represent standard deviation.