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. 2019 Jul 15;10(8):1228–1233. doi: 10.1021/acsmedchemlett.9b00274

Table 4. Potent N-Aryl Compounds with Reduced MRTs.

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a

TRPV4 IC50 is an average of at least two measurements.

b

DMPK properties are an average of measurements taken in two Sprague–Dawley rats.

c

Rat PPB fu is an average of at least two measurements.