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Internalization and endosome escape of M-PHMs/FAM-miR-124 complexes in activated RAW 264.7 cells. Internalization process and escape of M-PHMs loaded with FAM-miR-124 (green) from endosomes (red) of activated macrophages was visualized by confocal laser scanning microscopy (CLSM) at 1, 2, 4, and 6 h. The scale bar in the images was 10 μm.
