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OS and CSS for the high-grade LCNEC and SCLC patients in the surgery subgroup using Kaplan-Meier analysis and log-rank test. (A) OS in subgroup treated with surgery: LCNEC vs. SCLC, P < 0.001; (B) CSS in subgroup treated with surgery: LCNEC vs. SCLC, P < 0.001. Abbreviations: LCNEC, large cell neuroendocrine carcinoma; SCLC, small cell lung carcinoma; OS, overall survival; CSS, cancer-specific survival.
