Table 2.
Multivariate cox analyses of prognostic factors for overall and cancer-specific survival in the training cohort incorporating covariates identified by the smallest AIC value
| Characteristics | Overall Survival | Cancer-specific Survival | ||
|---|---|---|---|---|
| HR (95%CI) | P value | HR (95%CI) | P value | |
| Age (continuous variable) | ||||
| For every one year increase | 1.053(1.040-1.066) | <0.001*** | 1.039(1.023-1.055) | <0.001*** |
| Site | ||||
| Parotid | Reference | Not Included | ||
| Submandibular/Sublingual | 1.569(0.877-2.807) | 0.129 | ||
| Grade | ||||
| Low | Reference | Reference | ||
| Intermediate | 1.765(0.776-4.016) | 0.175 | 3.137(0.395-24.921) | 0.280 |
| High | 3.687(1.602-8.483) | 0.002** | 12.484(1.635-95.325) | 0.015** |
| T classification | ||||
| T1 | Reference | Reference | ||
| T2 | 0.880(0.498-1.554) | 0.658 | 0.958(0.395-2.325) | 0.924 |
| T3 | 2.102(1.234-3.582) | 0.006** | 2.509(1.144-5.502) | 0.022* |
| T4 | 2.607(1.581-4.298) | <0.001*** | 3.036(1.403-6.568) | 0.005** |
| N classification | ||||
| N0 | Reference | Reference | ||
| N1 | 1.805(1.127-2.893) | 0.005** | 3.348(1.763-6.358) | <0.001*** |
| N2 | 1.942(1.229-3.067) | 0.003** | 3.537(1.853-6.750) | <0.001*** |
| N3 | 3.352(1.010-11.123) | 0.048* | 4.772(1.053-21.625) | 0.043* |
| M classification | ||||
| M0 | Reference | Reference | ||
| M1 | 6.218(2.952-13.099) | <0.001*** | 5.301(2.287-12.288) | <0.001*** |
| Surgery | ||||
| Yes | Reference | Reference | ||
| No | 1.664(0.996-2.781) | 0.052 | 2.165(1.181-3.966) | 0.012* |
| Radiotherapy | ||||
| Received | Reference | Reference | ||
| No evidence | 1.458(0.963-2.208) | 0.074 | 1.603(0.886-2.899) | 0.119 |
* P <0.05; ** P <0.01;*** P <0.001