Table 3.
Performance of the ddPCR assay for detecting EGFR mutations in comparison with Tissue ARMS-PCR genotyping.
| cfDNA ddPCR | Tissue ARMS-PCR | Performance of ddPCR | ||||
|---|---|---|---|---|---|---|
| Positive | Negative | Sensitivity (%) | Specifity (%) | Concordance (%) | ||
| E746_A750del | Positive | 15 | 0 | 62.5 | 100 | 91.5 |
| Negative | 9 | 82 | ||||
| L858R | Positive | 15 | 5 | 75.0 | 94.2 | 90.6 |
| Negative | 5 | 81 | ||||