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. 2019 Jul 10;10(18):4341–4349. doi: 10.7150/jca.31326

Table 4.

Performance of the ddPCR assay for detecting cfDNA EGFR mutations in comparison with NGS.

cfDNA ddPCR NGS Concordance Kappa P
Positive Negative (%)
E746_A750del Positive 16 3 89.5
Negative 3 35 0.763 <0.001
L858R Positive 14 1 98.3
Negative 0 42 0.954 <0.001
T790M Positive 6 2
Negative 2 47 93.0 0.709 <0.001