Table 2.
Multivariate Cox logistic regression analysis of DFS in FUSCC and TCGA cohorts (DFS: disease-free survival; FUSCC: Fudan University Shanghai Cancer Center; TCGA: the Cancer Genome Atlas)
| Covariates | FUSCC | TCGA | |||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | ||
| Age (ref. <65 years) | 1.756 | 0.433-7.125 | 0.431 | 1.005 | 0.972-1.038 | 0.780 | |
| pT stage (ref. T1 - T2) | 18.506 | 2.706-126.551 | 0.003 | 2.026 | 1.101-3.728 | 0.023 | |
| pN stage (ref. N0) | 0.256 | 0.034-1.933 | 0.186 | 0.929 | 0.592-1.458 | 0.929 | |
| pM stage (ref. M0) | - | - | - | 0.475 | 0.149-1.514 | 0.208 | |
| AJCC stage (ref. I - II) | 0.724 | 0.137-4.124 | 0.724 | - | - | - | |
| Gleason score (ref. <7) | 2.518 | 0.797-7.959 | 0.116 | 3.202 | 3.202-2.013 | <0.001 | |
| MRE11 expression (ref. negative) | 8.588 | 1.015-72.667 | 0.048 | 1.071 | 0.687-1.669 | 0.763 | |