Table 3.
Univariate and multivariate Cox logistic regression analysis of OS in TCGA cohort (OS: overall survival; TCGA: the Cancer Genome Atlas)
| Covariates | Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | ||
| Age (ref. <65 years) | 1.053 | 0.955-1.160 | 0.300 | 1.064 | 0.952-1.188 | 0.276 | |
| pT stage (ref. T1 - T2) | 3.228 | 0.598-17.426 | 0.173 | 0.739 | 0.077-7.078 | 0.793 | |
| pN stage (ref. N0) | 2.408 | 0.629-9.226 | 0.200 | 1.775 | 0.365-8.636 | 0.477 | |
| pM stage (ref. M0) | 1.958 | 0.241-15.934 | 0.530 | - | - | 0.989 | |
| Gleason score (ref. <7) | 6.139 | 1.341-28.100 | 0.019 | 5.333 | 0.574-49.553 | 0.141 | |
| MRE11 expression (ref. negative) | 8.318 | 1.031-67.131 | 0.047 | 9.933 | 1.042-94.665 | 0.046 | |