Table 2.
Univariate and multivariate analyses of the overall survival of lung adenocarcinoma patients
| Clinicopathological features | Univariate analyses | Multivariate analyses | |||||
|---|---|---|---|---|---|---|---|
| HR | 95% (CI) | P value | HR | 95% (CI) | P value | ||
| Age (years) | ≤40 | 1.000 | 0.919-1.710 | 0.547 | |||
| >40 | 1.253 | ||||||
| Gender | Female | 1.000 | 0.825-1.536 | 0.457 | |||
| Male | 1.125 | ||||||
| TNM stage | Stage I - II | 1.000 | 1.577-3.076 | <0.001** | 1.000 | 1.546-3.021 | <0.001** |
| Stage III - IV | 3.591 | 2.161 | |||||
| Histological type | Mixed Subtype | 1.000 | 0.700-1.585 | 0.262 | |||
| Other Subtype | 1.053 | ||||||
| Tumour size | ≤3 cm | 1.000 | 1.692-3.181 | 0.017* | 1.000 | 1.246-1.729 | 0.175 |
| >3 cm | 2.458 | 1.685 | |||||
| DDX11 expression | Low | 1.000 | 1.783-2.983 | 0.024* | 1.000 | 1.536-2.966 | 0.036* |
| High | 2.334 | 2.021 | |||||
Notes: *P<0.05. **P<0.01.
Abbreviations: TNM: tumour-node-metastasis; HR: hazard ratio; CI: confidential interval; DDX11: DEAD/H-box helicase 11.