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. 2019 Jul 10;10(18):4293–4304. doi: 10.7150/jca.31829

Table 2.

Correlation between BOLA2 protein and clinicopathological characteristics in 175 HCC patients

Clinical and pathological variable BOLA2 protein
Low expression (n=57) High expression (n=118) P value
Age, years ≤60 36 64 0.264
>60 21 54
Sex Male 47 86 0.165
Female 10 32
Child-Pugh score A 38 93 0.083
B 19 25
Albumin, g/L ≤35 9 11 0.208
>35 48 107
AFP, (ng/mL) ≤200 26 41 0.258
>200 31 71
Liver cirrhosis Absent 10 12 0.168
Present 47 106
Tumor size, (cm) ≤5 24 36 0.130
>5 33 82
Tumor number Single 36 57 0.065
Multiple 21 61
Tumor encapsulation Complete 23 39 0.344
None 34 79
Satellite nodules Absent 42 33 <0.0001
Present 15 85
Venous invasion Absent 37 27 <0.0001
Present 20 91
Tumor differentiation I-II 9 49 0.001
III-IV 48 69
Tumor hemorrhage Absent 27 30 0.004
Present 30 88
BCLC stage A 31 35 0.002
B-C 26 83
TNM stage I 26 29 0.005
II-III 31 89

A significant difference is shown in bold.