Table 2.
Correlation between BOLA2 protein and clinicopathological characteristics in 175 HCC patients
| Clinical and pathological variable | BOLA2 protein | |||
|---|---|---|---|---|
| Low expression (n=57) | High expression (n=118) | P value | ||
| Age, years | ≤60 | 36 | 64 | 0.264 |
| >60 | 21 | 54 | ||
| Sex | Male | 47 | 86 | 0.165 |
| Female | 10 | 32 | ||
| Child-Pugh score | A | 38 | 93 | 0.083 |
| B | 19 | 25 | ||
| Albumin, g/L | ≤35 | 9 | 11 | 0.208 |
| >35 | 48 | 107 | ||
| AFP, (ng/mL) | ≤200 | 26 | 41 | 0.258 |
| >200 | 31 | 71 | ||
| Liver cirrhosis | Absent | 10 | 12 | 0.168 |
| Present | 47 | 106 | ||
| Tumor size, (cm) | ≤5 | 24 | 36 | 0.130 |
| >5 | 33 | 82 | ||
| Tumor number | Single | 36 | 57 | 0.065 |
| Multiple | 21 | 61 | ||
| Tumor encapsulation | Complete | 23 | 39 | 0.344 |
| None | 34 | 79 | ||
| Satellite nodules | Absent | 42 | 33 | <0.0001 |
| Present | 15 | 85 | ||
| Venous invasion | Absent | 37 | 27 | <0.0001 |
| Present | 20 | 91 | ||
| Tumor differentiation | I-II | 9 | 49 | 0.001 |
| III-IV | 48 | 69 | ||
| Tumor hemorrhage | Absent | 27 | 30 | 0.004 |
| Present | 30 | 88 | ||
| BCLC stage | A | 31 | 35 | 0.002 |
| B-C | 26 | 83 | ||
| TNM stage | I | 26 | 29 | 0.005 |
| II-III | 31 | 89 | ||
A significant difference is shown in bold.