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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Lancet Oncol. 2018 Nov 30;20(1):88–99. doi: 10.1016/S1470-2045(18)30621-1

Table 3:

Multivariable analysis for disease-free survival (DFS): NSABP B-42

Characteristic No. of patients (N=3,903) No. (%) of DFS events Hazards ratio (95%CI) P
Treatment Placebo 1953 339 (17.4) --- 0.0501
Letrozole 1950 292 (15.0) 0.86 (0.73,1.00)
Age < 60 1344 163 (12.1) --- <0.0001
≥60 2559 468 (18.3) 1.55 (1.29,1.86)
Pathologic Nodal Status Negative 2240 322 (14.4) --- 0.0005
Positive 1663 309 (18.6) 1.33 (1.13,1.56)
Received Tamoxifen No 2377 421 (17.7) --- 0.0035
Yes 1526 210 (13.8) 0.78 (0.66,0.92)
Surgery Type Lumpectomy 2374 348 (14.7) --- 0.0098
Mastectomy 1529 283 (18.5) 1.24 (1.05,1.45)