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. Author manuscript; available in PMC: 2019 Aug 13.
Published in final edited form as: Biol Reprod. 2018 Feb 1;98(2):239–249. doi: 10.1093/biolre/iox177

Table 2.

LOECs of category 1, category 2, and interassay control chemicals identified in the 96-well format of the Leydig cell assay.

Category 1 LOEC (μM)
Tamoxifen citrate 0.01
3,4,4’-Trichlorocarbanilide 0.1
Simvastatin 0.1
Cycloheximide 1
Metconazole 1
Flufenoxuron 1
Spirodiclofen 1
Flusilazole 10
17α-Ethynylestradiol 30
Corticosterone 100
Finasteride 100
Triphenyl phosphate 100
Category 2 LOEC LOEC (μM)
Dimethipin 1
1,4-Dihydroxy-2-naphthoic acid 3
4-Chloro-1,2-diaminobenzene 3
Anilazine 10
Hydroquinone 10
Interassay controls LOEC (μM)
Prochloraz 0.3
Bisphenol A 30
Dexamethasone 30