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. Author manuscript; available in PMC: 2019 Aug 13.
Published in final edited form as: J Neurol Sci. 2015 Jun 27;357(1-2):28–34. doi: 10.1016/j.jns.2015.06.055

Figure 3-.

Figure 3-

MRI of stroke lesion in NRG-1 and vehicle treated rats

The stroke lesions in the vehicle and treatment group at 3 hr and 48 hr post occlusion. In a rat in the vehicle group (65% CBF reduction during surgery), the stroke volumes are 327.3 mm3 and 660.3 mm3, respectively. In a rat in the treatment group, the ischemic region was only found in the striatum whereas no obvious ischemic region was seen in the cortex at 3 hr and 48 hr post occlusion. There was a 65% CBF reduction during the pMCAo surgery. In a rat with 95% CBF reduction, the ischemic region was only found in the striatum on 3 hr post occlusion. However, the ischemic regions expand to most of ipsilateral brain including cortex.