Table 3.

IC₅₀ of the synthesized compounds against cancer HepG-2 and normal THLE-2 liver cell lines.

Comp. No	IC50 (Mean ± SEM) (μg/mL) a
	HePG-2	THLE-2
3	12.60 ± 0.13	716.37 ± 0.10
4	4.22 ± 1.04	874.31 ± 0.22
5	31.81 ± 1.56	597.83 ± 0.14
6	14.42 ± 0.37	652.46 ± 0.03
7	23.61 ± 1.32	662.58 ± 0.17
9	5.60 ± 1.57	754.31 ± 0.20
10	16.72 ± 0.26	688.29 ± 0.11
12	9.11 ± 1.02	793.56 ± 0.31
14	34.80 ± 1.26	725.44 ± 0.15
16	7.50 ± 0.84	820.58 ± 0.18
17	9.92 ± 1.28	658.13 ± 0.25
Vinblastine b	4.63 ± 1.07	2146.05 ± 0.10

^aIC₅₀: compound concentration which inhibit cell proliferation by 50%.

^bpositive control, SEM: mean of the standard error; each value is the mean of three values.