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. 2019 Aug 6;10:1579. doi: 10.3389/fimmu.2019.01579

Table 2.

Twenty-seven significant SNPs genetic diversity and their Go function annotations.

Ref_ID SNPs Variants region He Ho PIC Gene locus
rs47045687 C > T Intergenic 0.3607 0.25 0.2957 id38041-LYPD6B
rs114843903 C > T Intergenic 0.5 0.3529 0.375 NYAP2-id50263
rs90835937 C > T Intergenic 0.4983 0.2941 0.3741 id84954-LOC100138140
rs5881560 T > C Intron 0.4082 0.3429 0.3249 OSBPL8
rs8678060 T > C Intron 0.4444 0.3333 0.3457 SYT1
rs37588412 T > C Intron 0.4444 0.2778 0.3457 LOC786089
rs75762330 C > T Intron 0.3673 0.303 0.2999 PTK2BΔ
rs88640083 A > G Intergenic 0.1847 0.2059 0.1676 SYKΔ-DIRAS2
rs17176625 C > T Intergenic 0.4824 0.3125 0.3661 LOC-100295568-HTR1B
rs17514753 T > C Intergenic 0.4775 0.4848 0.3635 TRNAA-UGC-MEI4
rs17518215 C > T Intergenic 0.4844 0.5294 0.3671 TRNAA-UGC-MEI4
rs22015301 G > C Downstream 0.405 0.359 0.323 id241467
rs98519900 G > A Intergenic 0.5 0.2727 0.375 PARK2-PARK2
rs14802054 A > G Intron 0.4927 0.4545 0.3713 TSC22D1
rs25949166 A > G Intron 0.4097 0.325 0.3258 PRTFDC1
rs33866959 A > T Intron 0.4824 0.25 0.3661 CPA6
rs48577224 T > C Intergenic 0.4965 0.3611 0.3733 NPHP4-LOC100297820
rs49099498 G > A Intergenic 0.375 0.1842 0.3047 NPHP4-LOC100297820
rs27017918 G > A Intergenic 0.2945 0.2564 0.2512 LOC100138242-TRNAW-CCA
rs32265465 T > C Intergenic 0.4244 0.2778 0.3343 LOC789319-CDH11
rs9704351 C > G Intergenic 0.382 0.4 0.3091 MAP1B-CARTPT
rs20438858 G > A Intron 0.4284 0.2432 0.3366 TNFRSF21Δ
rs22490040 C > T Intergenic 0.4761 0.3438 0.3628 DEFB112-TFAP2D
rs28580132 A > G 3′-UTR 0.4761 0.2812 0.3628 LOC785873
rs3233588 G > A Upstream 0.4284 0.4595 0.3366 id550612
rs1988979 G > A Intron 0.4269 0.2059 0.3358 TBC1D24
rs50888452 G > A Intron 0.4995 0.3438 0.3748 SRPX2

He, Heterozygosity Expectation; Ho, Heterozygosity Observation; PIC, Polymorphism Information Content.

Δ

Three significant SNPs were annotated to the immune-regulated genes, respectively.