Table 26.3.
Protein kinases | MFN phosphorylation sites | Effect on mitophagy |
---|---|---|
PINK1 | T111 of MFN2 | Activation |
PINK1 | S442 of MFN2 | Activation |
JNK | Ser27 of MFN2 | Inhibition |
ERK | T562 of MFN1 | Inhibition |
Protein kinases | MFN phosphorylation sites | Effect on mitophagy |
---|---|---|
PINK1 | T111 of MFN2 | Activation |
PINK1 | S442 of MFN2 | Activation |
JNK | Ser27 of MFN2 | Inhibition |
ERK | T562 of MFN1 | Inhibition |