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. Author manuscript; available in PMC: 2019 Nov 21.
Published in final edited form as: Bioconjug Chem. 2018 Oct 16;29(11):3626–3637. doi: 10.1021/acs.bioconjchem.8b00564

Figure 3.

Figure 3.

In vivo binding of CAM targeted click liposomes shows specificity to target cells vs wild type cells. Flow cytometry data graphed as mean fluorescence values of scFv and mAb click conjugated fluorescent liposomes targeted to designated CAMs at varying concentrations. (a,b) YN1 mAb (a) and scFv (b) liposomes binding to REN mouse ICAM cells versus REN WT. (c,d) R6.5 mAb (c) and scFv (d) liposomes show specific binding to CHO human ICAM cells versus CHO WT. (e,f) 390 mAb (e) and scFv (f) liposomes binding to REN mouse PECAM cells versus REN WT. Error bars represent standard deviation, n = 2.