Table 3.

A Comparison of the Two Main Subgroups of Patients

Group	Age at disease onset (years)	Age at the first BoNT injection (years)	Age at the time of post-treatment evaluation (years)	Number of tremor modes treated (per limb)	BoNT dose (Abo units per limb)
Essential tremor	45.20 ± 19.47 50.5 (13–82)	67.38 ± 68.14 67.0 (48–87)	70.67 ± 8.38 70.0 (49–88)	1.90 ± 0.71 2.0 (1–4)	95.43 ± 54.07 85.0 (12–220)
Holmes tremor	36.50 ± 17.17 30.5 (18–62)	40.38 ± 19.26 37.0 (21–69)	49.38 ± 17.59 49.0 (20–74)	2.88 ± 1.55 3.0 (1–5)	216.13 ± 127.93 212.5 (54–390)
t-value (p) in Student’s t-test	1.17 (NS)	5.39 (p < 10-3)	8.24 (p = .01)	-1.73 (NS)	-2.60 (p = .03)

Abbreviations: Abo, abobotulinumtoxin A; BoNT, botulinum neurotoxin; NS, not significant.

All descriptive data are quoted as the mean ± standard deviation and the median (range).