Table 3.

Number of drug target genes identified for CHi-C genes enriched in significant pathways (Benjamini-Hochberg) for each disease, corresponding to the number of drugs and the potential for non-existing pathway gene targets for drug repositioning

Disease	Genes identified by CHi-C (n)	Genes which are existing drug targets (n)	Drugs identified (n)	Drugs currently used (n)	Drugs for potential repositioning (n)	Potential pathway targets (n)	Potential pathway drugs (n)
RA	50	13	38	8	30	283	398
PsA	9	2	2	0	2	47	87
JIA	10	2	4	0	4	205	325
All	59	14	39	8	31	307	412

CHi-C, Capture Hi-C; JIA, juvenile idiopathic arthritis; PsA, psoriatic arthritis; RA, rheumatoid arthritis.