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. 2019 Aug 9;12:6297–6307. doi: 10.2147/OTT.S214689

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© 2019 Sun et al.

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MALAT1 activated JAK2/STAT3 pathway.

Notes: (A) Total cell lysates were collected and immunoblotted with the indicated antibodies. β-Actin was used as a loading control. Graphs are presented as the mean density of p-JAK2 and p-STAT3 normalized against the mean density of JAK2 or STAT3 from three independent experiments (presented as relative density of phosphoprotein vs total protein). Data are presented as the mean ± standard error of the mean (n=3). *P<0.05, **P<0.01, ***P<0.001 compared to untreated control cells at 0 min.

Abbreviations: MALAT1, metastasis-associated lung adenocarcinoma transcript 1; si-MALAT1, MALAT1 small interfering RNA; si-NC, noncoding small interfering RNA.