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. 2019 May 30;14(9):850–876. doi: 10.1080/15592294.2019.1615357

Figure 6.

Figure 6.

Bovine muscle differentially expressed miRNAs (DE-miRNAs) enriched KEGG signalling pathways and its corroboration with human data. KEGG pathways were enriched by DAVID with predicted mRNA targets of DE-miRNAs in LOS muscle. Pathways associated with several important biological functions are illustrated. mirPath and human library of TarBase was used to corroborate bovine prediction results. Green hexagons = pathways detected significantly (corrected p value < 0.05) in bovine but not shown in human results. Orange hexagons = significant bovine pathways that were also confirmed by human results. Blue circle = important biological functions associated with development and growth. Dashed lines = link pathways to their biological functions. Solid arrows = link pathways to their downstream pathways. The upper and lower corners of the hexagons on both sides connect the upstream pathways, and the middle corners connect the downstream pathways or biological functions.