Table 3.
Muscle DE-miRNAs with DMRs in upstream region of predicted TSS.
|
Bovine miRNA TSS prediction based on human database mirTrans | ||||||||||
|
Bovine |
Human |
|||||||||
|
Pre-miRNA |
DE-miRNA |
Chr. |
Strand |
Predicted TSS regions |
DMRs (10 kb upstream) |
Pre-miRNA |
Chr. |
Strand |
TSS regions |
TSS numbers |
| bta-mir-132 | bta-miR-132 | 19 | - | 23651124-23652605 | 23658550-23659389 hypo-methylation | hsa-mir-132 | 17 | - | 2049750-2051271 | 6 |
| 23654400-23655941 | 2053392-2055221 | 5 | ||||||||
| 23655550-23656356 | 2054780-2055780 | 1 | ||||||||
| |
|
|
|
23659251-23660616 |
|
|
|
|
2058698-2059698 |
1 |
| bta-mir-196a-2 | bta-miR-196a | 5 | - | 26205331-26205996 | 26213420-26215619 hypo-methylation | hsa-mir-196a-2 | 12 | + | 53985345-53986345 | 1 |
| |
|
|
|
26204650-26205506 |
|
|
|
|
53985933-53986933 |
1 |
|
Bovine miRNA TSS prediction based on human database miRStart | ||||||||||
|
Bovine |
Human |
|||||||||
|
Pre-miRNA |
DE-miRNA |
Chr. |
Strand |
Predicted TSS regions |
DMRs (10 kb upstream) |
Pre-miRNA |
Chr. |
Strand |
TSS regions |
TSS numbers |
| bta-mir-132 | bta-miR-132 | 19 | - | 23651124-23652234 | 23658550-23659389 hypo-methylation | hsa-mir-132 | 17 | - | 1952818-1954251 | 2 |
| 23652410-23653246 | 1954267-1955267 | 1 | ||||||||
| 23656460-23658263 | 1959006-1961027 | 5 | ||||||||
| 23657985-23658829 | 1960569-1961569 | 1 | ||||||||
| |
|
|
|
23658965-23660332 |
|
|
|
|
1961706-1962706 |
1 |
| bta-mir-196a-1 |
bta-miR-196a |
19 |
+ |
38495732-38496157 |
38493580-38494349 hypo-methylation |
hsa-mir-196a-1 |
17 |
- |
46710434-46711434 |
1 |
| bta-mir-196a-2 | bta-miR-196a | 5 | - | 26224532-26225761 | 26222020-26225019 hypo-methylation; 26226320-26228319 hypo-methylation | hsa-mir-196a-2 | 12 | + | 54359273-54360486 | 2 |
| |
|
|
|
26216530-26217547 |
|
|
|
|
54367586-54368646 |
2 |
| bta-mir-196a-2 | bta-miR-196a | 5 | - | 26210597-26211395 | 26213420-26215619 hypo-methylation | hsa-mir-196a-2 | 12 | + | 54373662-54374662 | 1 |
| |
|
|
|
26204238-26205212 |
|
|
|
|
54379926-54381208 |
2 |
| bta-mir-26a-1 |
bta-miR-26a |
22 |
+ |
11436811-11437037 |
11430423-11431382 hyper-methylation |
hsa-mir-26a-1 |
3 |
+ |
37984525-37985525 |
1 |
| bta-mir-296 | bta-miR-296-3p | 13 | + | 58054240-58054654 | 58046118-58046817 hyper-methylation; 58048708-58049757 hyper-methylation | hsa-mir-296 | 20 | - | 57408489-57409674 | 3 |
| 58053302-58053794 | 57409262-57410262 | 1 | ||||||||
Chr. = chromosome. Predicted TSS regions: conserved region in bovine of human TSS region of the conserved miRNAs. TSS regions: region of adjacent TSS (within 500bp) + 500bp in both up- and downstream.