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. 2019 Aug 13;14(8):e0221036. doi: 10.1371/journal.pone.0221036

Table 3. DANA and biomarker concentrations before and after overpressure exposure.

DANA (milliseconds) Pre-Exp Post-Exp % Change p-value
Median IQR Median IQR
SRT 269.0 256.6–305.7 299.9 273.5–330.6 11.5 0.048*
PRT 636.9 592.9–672.1 633.7 601.5–698.7 -0.50 0.398
GNG 604.7 554.0–655.7 597.6 560.1–668.4 -1.17 0.475
Serum Biomarker (pg/mL) Pre-Exp Post-Exp % Change p-value
Median IQR Median IQR
GFAP 59.2 45.3–70.2 52.1 44.0–70.2 -12.0 0.051
UCH-L1 7.83 2.53–22.1 7.07 3.00–20.5 -9.71 0.978
Nf-L 4.90 3.77–6.71 5.23 3.73–7.58 6.73 0.035*
Tau 0.07 0–0.22 0.122 0–0.23 64.9 0.090
Aβ-40 126 92.1–160.0 140 104.5–164.5 11.1 0.151
Aβ-42 5.09 2.47–6.55 5.19 3.80–7.01 1.96 0.046*

The quantitative values of DANA neurocognitive tests (simple reaction time, procedural reaction time (PRT), and Go—No Go time, milliseconds) and serum biomarkers (GFAP, UCH-L1, Nf-L, tau, Aβ-40, and Aβ-42 [pg/mL] derived from subjects tested before (pre-) and after (post-) overpressure exposure are indicated. Values are displayed as the median and IQR.