Skip to main content
. 2019 Aug 13;14(8):e0221130. doi: 10.1371/journal.pone.0221130

Table 2. Characteristics of the study population.

Case group Control group
Number of patients 13 (100) 100 (100)
Sex
    Male 8 (61.5) 41 (41.0)
    Female 5 (38.5) 59 (59.0)
Age, years 56.4 (15.9) 52.9 (21.8)
Agreement between diagnosis with ICD-10 code and final diagnosis 8 (61.5) 85 (85.0)
Referral from another hospital 1 (7.7) 24 (24.0)
Clinical course for SJS/TEN at the Department of Dermatology
    Item 2: Hospitalization 13 (100) 32 (32.0)
    Item 3: Skin biopsy 12 (92.3) 12 (12.0)
    Item 4: Systemic treatment for SJS/TEN 12 (92.3) 8 (8.0)
        Steroid therapy 12 (92.3) 8 (8.0)
        Intravenous immunoglobulin therapy 3 (23.1) 0 (0.0)
        Plasma exchange therapy 0 (0.0) 0 (0.0)
Medical encounters for mucocutaneous lesions from SJS/TEN
    Item 5: Presence of medical encounters for mucocutaneous lesions from SJS/TEN 12 (92.3) 6 (6.0)
        ICD-10 code for SJS/TEN at the Department of Ophthalmology or Dentistry, or for mucocutaneous lesions (no limitation on department) 11 (84.6) 2 (2.0)
        Steroid eyedrops or ophthalmic ointment 8 (61.5) 2 (2.0)
        Slit-lamp microscopy 10 (76.9) 6 (6.0)
Exclusion of paraneoplastic pemphigus
    Item 6a: Prescription of anti-cancer drug 2 (15.4) 12 (12.0)
    Item 6b: Anti-desmoglein 1 or 3 antibody test ≥2 0 (0.0) 2 (2.0)

ICD-10, International Classification of Diseases, 10th Edition; SJS, Stevens-Johnson syndrome; TEN, toxic epidermal necrolysis.

Data are presented as mean (SD) or number of subjects (%).