Table 2.
Variable | Hazard ratio | 95%CI | p-Value |
---|---|---|---|
Clinical/angiographic variables | |||
Age | 1.05 | 1.02–1.09 | 0.001 |
Male | 1.78 | 0.68–4.66 | 0.243 |
BMI | 1.05 | 1.03–1.09 | 0.038 |
Smoking | 1.96 | 0.93–4.13 | 0.074 |
Hypertension | 1.76 | 0.86–3.63 | 0.124 |
Dyslipidemia | 1.13 | 0.52–2.22 | 0.734 |
Diabetes | 2.90 | 1.38–6.06 | 0.005 |
Chronic kidney disease | 6.59 | 3.13–13.89 | <0.001 |
Stroke/TIA | 1.54 | 0.88–4.12 | 0.212 |
Post-PCI TIMI flow | 1.43 | 0.64–3.12 | 0.332 |
No of diseased vessels | 2.08 | 1.40–3.10 | <0.001 |
Infarct type (STEMI) | 1.53 | 0.62–3.75 | 0.347 |
LV and RV size and function | |||
LVEF | 0.96 | 0.92–0.99 | 0.030 |
LVEDVi | 1.03 | 1.01–1.05 | 0.009 |
LVESVi | 1.02 | 0.99–1.02 | 0.611 |
LVMI | 1.77 | 1.06–2.71 | 0.049 |
RV S′ | 1.04 | 0.90–1.12 | 0.938 |
Guideline recommended diastolic parameters | |||
E/A > 2 | 1.36 | 0.17–10.0 | 0.759 |
Average E/e′ > 14 | 3.41 | 1.59–7.28 | 0.002 |
TR Velocity > 2.8 m/s | 1.76 | 0.92–3.14 | 0.155 |
LAVI >34 ml/m2 | 3.22 | 1.57–6.67 | 0.001 |
Significant (grade 2/3) DD | 3.97 | 1.86–8.47 | <0.001 |
Discharge medications | |||
Aspirin | 0.74 | 0.22–3.12 | 0.718 |
Beta-blocker | 1.04 | 0.61–2.19 | 0.927 |
ACE-inhibitor/ARB blocker | 0.55 | 0.25–1.25 | 0.076 |
Statin | 0.90 | 0.24–3.23 | 0.562 |
Dual antiplatelet therapy | 0.54 | 0.29–0.99 | 0.049 |
MACE = major adverse cardiovascular events; BMI = body mass index; STEMI = ST elevation MI; BMI = body mass index; LV = left ventricular; LVEF = left ventricular ejection fraction; LVEDVi = left ventricular end diastolic volume index; LVESVi = left ventricular end systolic volume index; E/A = ratio of mitral E wave to A wave; E/e′ = ratio of mitral E wave to e′; TR = tricuspid regurgitation; LAVI = left atrial volume index; DD2016 = diastolic dysfunction by 2016 guidelines; DD2009 = diastolic dysfunction by 2009 guidelines.