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. Author manuscript; available in PMC: 2020 Jun 4.
Published in final edited form as: J Peripher Nerv Syst. 2019 Jun 4;24(2):195–206. doi: 10.1111/jns.12326

Figure 5. Peripheral nerve cell-specific structural proteins.

Figure 5.

Representative indirect fluorescent digital photomicrographs of cryostat axial sections of normal adult sural nerves show UEA-1-positive endothelial cells (green; A, E, I, M, Q) with expression of PCDH1, CD44, ACTG1, CALD1 and MYO10 (red; B, F, J, N, R respectively) on endoneurial microvessels, fenestrated epineurial macrovessels, perineurium and Schwann cells (PCDH1) and axons (CD44, ACTG1, CALD1 and MYO10), shown in the merged images at lower and higher magnifications (yellow/ orange for endothelial cells). Expression of these proteins by these cell types implies roles in maintaining the structural integrity of peripheral nerve specific cells in normal adult nerves. White arrows demonstrate positively staining endoneurial microvessels. Blue (DAPI) staining indicates nuclei. Scale bar 500 μm for A-C, E-G, I-K, M-O, and Q-S and 125 μm for D, H, L, P and T.