Author response image 4. The VPs of rotavirus present a ring-like structure at early times of infection.

MA104 cells grown in coverslips were infected with RRV (MOI of 3). At 3 hours post-infection, the cells were fixed and co-inmunostained with the indicate antibodies. The nanoscale distribution of viral proteins within the VP was then analyzed through SRRF-SRM. Scale bar is 0.5 um.