Figure 6:

Representative H&E sections. (A) Non-tumor bearing mice. (B) Untreated tumor-bearing mice, week 4. (C) Treated tumor-bearing mice, week 6. Green outline indicates tumor boundaries. Top inset highlights non-tumor cells, as indicated by the presence of large, cytoplasm-rich, multi-nucleated megakaryocytes (red arrowhead) and lobular, concave nuclei (red arrow). The bottom inset highlights tumor cells, as indicated by the presence of segmented, chromatin-rich mitoses (green arrowhead) and oval plasma cell nuclei (green arrow). Scale bar, 500 μm; inset scale bar, 20 μm.