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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Anesthesiology. 2019 Sep;131(3):477–491. doi: 10.1097/ALN.0000000000002729

Table 2.

Sociodemographic and Clinical Characteristics

Stratified by POD and POCD at 2 Months (N=536)
Characteristics Total Study Sample* POD−
POCD−
POD+
POCD−
POD−
POCD+
POD+
POCD+
Number of observations [N (%)] 551 319 95 91 31
Age (years) [mean (SD)] 77 (5) 76 (5) 77 (5) 77 (5) 78 (5)
Sex [n (%)]
Men 231 (42) 129 (40) 37 (39) 47 (52) 13 (42)
Women 320 (58) 190 (60) 58 (61) 44 (48) 18 (58)
Race [n (%)]
White 510 (93) 298 (93) 84 (88) 85 (93) 29 (94)
All other race and ethnicity groups 41 (7) 21 (7) 12 (13) 6 (6) 1 (4)
Education (years) [mean (SD)] 15 (3) 15 (3) 15 (3) 14 (3) 14 (2)
3MS Score [mean (SD)] 93.6 (5.3) 94.5 (4.8) 91.6 (5.7) 92.7 (5.8) 92.5 (5.9)
General cognitive performance, (GCP) [mean (SD)] 57.7 (7.2) 58.9 (7.2) 54.7 (6.3) 57.5 (7.4) 55.6 (6.7)
Proxy IQCODE [mean (SD)] 3.1 (0.2) 3.1 (0.2) 3.2 (0.3) 3.1 (0.2) 3.3 (0.3)
Charlson Comorbidity Index, [mean (SD)] 1.02 (1.3) 0.90 (1.2) 1.29 (1.3) 1.14 (1.3) 1.10 (1.4)
Surgery type [n (%)]
Orthopedic 446 (81) 265 (83) 74 (78) 72 (79) 24 (77)
Vascular 34 (6) 13 (4) 8.5 (9) 8.7 (10) 1.5 (5)
Gastrointestinal 71 (13) 41 (13) 13 (14) 10 (11) 5.2 (17)
Anesthesia type [n (%)]
General 455 (85) 265 (84) 83 (87) 78 (86) 29 (97)
Spinal 77 (14) 52 (16) 12 (13) 12 (13) 1 (3)
General & Spinal 4 (1) 2 (1) 0 (0) 1 (1) 0 (0)
Duration of surgery (minutes) [mean (SD)] 144 (77) 133 (67) 166 (88) 153 (87) 157 (79)
Duration of anesthesia (minutes) [mean (SD)] 193 (81) 182 (73) 219 (96) 202 (85) 204 (77)
*

N=551, baseline characteristics, excludes those who had died or were lost to follow-up at 2 months.

POCD = postoperative cognitive dysfunction, proportions estimated from multiply-imputed data; POD = postoperative delirium; 3MS = Modified Mini-Mental State.