Table 1.

Summary of stress effects

	Summary of Stress Effects1
	SPS	SPS break	6hr URS	2hr URS
EPM (anxiety)	↑	−/↑	↑	−
NSF (anxiety)	↑	−/↑	↑	−
Object location	↓	↓	−	↓
Extinction (fear)	−	−	↑	↓
Fear recovery	↑	−	↑	−
dCA1 Volume	−	−	↓	−
vCA1 Volume	↓	−/↓	↓	−

¹Symbols show changes relative to unstressed controls. A single symbol indicates effects are the same in wild type (WT) and TK rats; different effects are shown as WT/TK. ↑, increase relative to unstressed; ↓,decrease; – no change. SPS, single prolonged stress; URS, unpredictable restraint stress; EPM, elevated plus maze; NSF, novelty-suppressed feeding.