Figure 1. IL37 gene expression of whole blood cells from healthy individuals and melanoma patients.
(A) qRT-PCR was conducted using mRNAs extracted from PAX-gene-collected whole blood samples from 49 healthy individuals and 49 melanoma patients. (B) qRT-PCR of IL-37 from PAX-gene-collected whole blood samples from 49 melanoma patients in different stages of melanoma: stage 0 (n = 5), stage I (n = 18), stage II (n = 10), stage III (n = 6), and stage IV (n = 10). IL-37 gene expression was determined based on the relative levels to GAPDH mRNA. Each symbol represents an individual sample; horizontal lines indicate mean ± SEM. * p < 0.05 (Student’s t-test).