Table 1.

Clinical characteristics of LSCC patients from whom UM-SCC cell lines were derived. UM-SCC-10A and 10B were derived from samples taken from the same patient at different times and sites. UM-SCC-81A and 81B were derived from two vocal cord masses resected in separate procedures. HPV-18 was detected in UM-SCC-105 by HPV-PCR mass array. HPV was not detected in other cell lines. Categories for which no data was available are marked with a dash; M, male; F, female; P, primary; R, recurrence; Met, metastasis; ICX, induction chemotherapy; S, surgery; RT, radiation therapy.

Cell Line	Age	Sex	Clinical TNM	Stage	Specimen site	Type of Lesion	Previous Therapy	HPV Status	Smoking (pack-years)	Alcohol
UMSCC-10A	57	M	T3N0M0	III	True Cord	P	None		20	Heavy
UMSCC-10B	58	M	rT3N1M0	III	Lymph Node	Met	S		20	Heavy
UMSCC-11A	65	M	T2N2aM0	IV	Epiglottis	P	ICX		35	Heavy
UMSCC-12	71	M	T2N1M0	III	Larynx	R	S, RT		-	-
UMSCC-13	60	M	T3N0M0	III	Stoma	R	RT,S		90	Heavy
UMSCC-17B	47	F	T1N1M0	III	Soft tissue-neck	Met	RT		40	None
UMSCC-23	36	F	T2N0M0	II	Supraglottis	P	None		48	Heavy
UMSCC-25	50	M	rT3N2bM0	III	Lymph Node	Met	RT,S,S		Heavy	Heavy
UMSCC-28	61	F	T1N0M0	I	True Cord	P	None		40	-
UMSCC-41	78	M	T2N1M0	III	Arytenoid	P	None		50	Moderate
UMSCC-46	58	F	T2N2M0	IV	Supraglottis	R	RT,S		60	Heavy
UMSCC-57	69	M	-	-	Supraglottis	-	-		-	-
UMSCC-76	66	M	T3N2cM0	IV	Lymph Node	Met	ICX		40	Heavy
UMSCC-81A	53	M	T2N0M0	II	Anterior Commisure	P	None		100	Heavy
UMSCC-81B	58	M	T2N0M0	II	True Cord	P	None		100	Heavy
UMSCC-105	51	M	T4N0M0	IV	True Cord	P	None	HPV-18	0	None