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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: J Intensive Care Med. 2019 Feb 13;35(12):1453–1464. doi: 10.1177/0885066619828293

Figure 1.

Figure 1

A, B, Calculation of the cerebral oximetry index (COx) in a 71-year-old man with septic shock from disseminated Nocardia. When mean arterial pressure (MAP) was approximately 55 to 90 mm Hg, MAP and regional cerebral oxygen saturation (rScO2) measured by near-infrared spectroscopy were positively correlated. The positive correlation yielded a COx value of 0.78, indicating pressure-passive cerebral blood flow with impaired autoregulation. The linear regression line is illustrated (E[Y] = 48.1+0.16X; 95% confidence interval for slope: 0.15, 0.17; P < .001). C, D, Calculation of COx in a 69-year-old patient with septic shock from Clostridium difficile colitis. When MAP was approximately 80–100 mm Hg, MAP and rScO2 were negatively correlated. This negative correlation resulted in a COx value of ‒0.42, indicating pressure-reactive cerebral blood flow with functional autoregulation. The linear regression line is illustrated (E[Y] = 74.54–0.29X; 95% confidence interval for slope: ‒0.35, ‒0.22; P < .001).