Table 4.

Associations between the level of humoral Epstein-Barr virus response (anti-EBNA-1 titer) and magnetization transfer ratio outcome measures in relapsing-remitting and progressive multiple sclerosis patients.

	RRMS (n=69)			SPMS (n=32)
	rs-value	p-value	BH-adjusted p-value	rs-value	p-value	BH-adjusted p-value
T2 lesion MTR	−0.261	0.037	0.124	−0.132	0.487	0.812
T1 lesion MTR	−0.524	<0.001	0.001	−0.075	0.716	0.895
NABT MTR	−0.227	0.062	0.178	−0.066	0.723	0.851
NAWM MTR	−0.164	0.180	0.451	−0.112	0.550	0.847
NAGM MTR	−0.308	0.011	0.043	−0.068	0.715	0.953

RRMS – relapsing-remitting multiple sclerosis, SPMS – secondary-progressive multiple sclerosis, MTR – magnetization transfer ratio, NABT – normal appearing brain tissue, NAWM – normal appearing white matter, NAGM – normal appearing gray matter.

Partial non-parametric correlation adjusted for scanner field strength were used. Benjamini-Hochberg-adjusted p values <0.05 were considered significant.