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. 2019 Aug 13;9:11800. doi: 10.1038/s41598-019-48089-1

Table 1.

Expression of regulatory genes in WNT, TGF-β, JNK, HedgeHog and ERK1/2 pathways.

Gene Control Count (CC) Control FPKM Osteo Count (OC) Osteo FPKM Fold Change (OC/CC)
WNT11 54.00 0.74 97.62 1.31 1.81
WNT5B 1791.93 25.60 3114.00 45.28 1.74
FZD6 1684.02 12.67 1581.63 12.35 0.94
FZD7 985.96 6.43 736.56 4.76 0.75
ROR2 983.81 6.29 3785.68 28.58 3.85
LEF1 9.00 0.29 37.00 0.35 4.11
LRP5 1447.00 7.45 2823.46 14.13 1.95
WNT9A 50.03 0.32 5.00 0.03 0.10
SFRP2 19264.29 247.69 2656.32 33.81 0.14
CTNNB1 4602.24 45.58 7320.38 78.25 1.59
GSK3B 1124.98 8.46 1519.08 10.62 1.35
AXIN1 580.00 4.15 717.62 5.39 1.24
AXIN2 222.85 2.71 222.74 2.18 1.00
DVL1 2227.00 22.56 1581.09 15.28 0.71
DVL2 1759.84 21.04 3116.55 38.01 1.77
SMAD2 2143.02 28.33 2968.44 43.56 1.39
SMAD3 5425.58 39.72 5155.08 37.06 0.95
SMAD7 2198.90 24.34 633.34 8.12 0.29
TGFB1 4702.29 71.86 2142.55 37.60 0.46
TGFB2 80.00 0.83 118.60 0.58 1.48
TGFBR1 4759.46 41.74 3530.18 34.88 0.74
TGFBR2 14775.10 79.97 41096.61 220.77 2.78
PTH1R 79.00 2.06 117.00 2.06 1.48
PRKACA 429.83 4.60 794.39 9.58 1.85
FOS 107.00 1.50 323.40 4.24 3.02
JUN 1333.68 9.51 2454.04 17.36 1.84
MAPK8 566.99 17.71 385.81 11.92 0.68
MAPK9 1644.04 14.31 1702.58 15.01 1.04
MAPK10 29.00 0.40 53.71 0.65 1.85
PTCH1 135.29 1.25 337.14 3.01 2.49
GLI2 764.97 13.16 220.89 4.16 0.29
GLI3 908.90 6.03 1992.76 13.80 2.19
MAP2K1 2835.54 28.45 2462.08 25.17 0.87
MAP2K2 4909.45 106.62 6965.68 146.39 1.42
MAPK1 10938.19 127.56 8654.65 100.43 0.79
MAPK3 925.06 15.90 1719.48 30.11 1.86