Table 1.
Baseline characteristics of included patients (n = 32).
| Characteristics | Median | Range (min–max) |
|---|---|---|
| Age (yr) | 52 | 20–70 |
| Sex (male)a | 20 | 63% |
| Weight (kg) | 62.7 | 43.9–102.4 |
| Height (cm) | 165.8 | 151–180 |
| Hemoglobin (g/dL) | 14.1 | 10.6–17.5 |
| Hematocrit (%) | 43.6 | 32.3–53.8 |
| Serum creatinine (mg/dL) | 1.22 | 0.69–1.66 |
| MDRD eGFR (mL/min/1.73 m2) | 59.5 | 35.0–85.7 |
| Albumin (g/dL) | 4.4 | 3.8–5.0 |
| Total bilirubin (mg/dL) | 0.7 | 0.5–2.4 |
| Tacrolimus daily dose (mg) | 2 | 1–6 |
| Mycophenolate mofetil daily dose (mg) | 1,000 | 500–2,000 |
| Prednisolone daily dose (mg)b | 5 | 2.5–5 |
| Post-operative days (yr) | 5.7 | 0.6–10.4 |
| Collected blood samples per patients | 4 | 1–5 |
| CYP3A5 (rs776746) expressera | 13 | 40.6% |
| SLCO1B3 (rs4149117) T carriera | 15 | 46.9% |
| UGT2B7 (rs7439366) T carriera | 15 | 46.9% |
aSex and CYP3A5 expresser are presented as number and proportion; bPrednisolone or its equivalent; CYP3A5 expresser, CYP3A5 *1/*1 or CYP3A5 *1/*3 carriers; MDRD, modification of diet in renal disease; eGFR, estimated glomerular filtration rate.