Table 1.
Demographic and clinical characteristics of the cohort.
| Characteristics | All | Bacterial | Viral | Control | Bacterial vs. Viral (P-value) |
|---|---|---|---|---|---|
| n | 35 | 14 | 11 | 10 | — |
| Age; median (IQR) | 2.2 (1.4–8.7) | 2.3 (1.2–8.7) | 3.5 (1.0–6.4) | 1.6 (1.5–8.5) | 0.809 |
| Sex (% Female/Male) | (43/57) | (36/64) | (45/ 55) | (50/50) | 0.697 |
| Admitted to hospital (%) | 84 | 93 | 72 | — | — |
| PICU (%) | 43 | 54 | 25 | — | — |
| Admission time (days); median (IQR) | 8.0 (6.0–13.0) | 10.0 (10.0–15.0) | 6.5 (5.5–7.0) | — | — |
| C-reactive protein (mg/L); median (IQR) | 46.0 (19.0–241.0) | 190.1 (71.25–198.8) | 9.6 (4.2–43.5) | — | — |
| Neutrophils; median (IQR) | 11.1 (7.5–14.6) | 11.6 (7.6–14.8) | 10.2 (6.2–13.3) | — | 0.250 |
| Lymphocytes; median (IQR) | 1.7 (0.8–4.0) | 1.4 (0.7–3.4) | 2.4 (1.0–3.8) | — | 0.654 |
| Monocytes; median (IQR) | 0.8 (0.4–1.2) | 1.1 (0.6–2.0) | 0.6 (0.3–1.0) | — | 0.072 |
| Days from symptoms (fever) to blood collection; mean | 2.36 | 2.64 | 2.00 | — | — |
| Maximum Tª before admission; median (IQR) | 39.0 (38.2–39.5) | 39.1 (38.6–39.9) | 39.0 (38.1–39.1) | — | — |
| Pathogens (%) | |||||
| Neisseria meningitidis | — | 42.9 | — | — | — |
| Streptococcus pneumoniae | — | 14.3 | — | — | — |
| Escherichia Coli | — | 21.4 | — | — | — |
| Staphylococcus aureus | — | 14.3 | — | — | — |
| Group A Streptococcus pyogenes | — | 7.1 | — | — | — |
| Enterovirus | — | — | 36.3 | — | — |
| Respiratory syncytial virus | — | — | 27.3 | — | — |
| Influenza A | — | — | 18.2 | — | — |
| Adenovirus | — | — | 18.2 | — | — |