Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Aug 7;10:1866. doi: 10.3389/fimmu.2019.01866

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Zheng, Liang, Xu, Li, Luo, Wu, Li, Tang, Zhong, Chen, Yang, Sun, Zhang and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Increased C5aR1 expression on pDCs from psoriasis patients. Skin tissues and PBMCs of psoriatic patients and healthy individuals were collected. (A) Immunofluorescence staining for C5aR1 expression (red) on pDCs (stained with anti-CD123) (green) in skin tissues. Nuclei (blue) were stained with Hoechst 33258. Arrows indicate cells positively stained for both C5aR1 and CD123. Scale bar = 5 μm. Right: Quantification of C5aR1⁺ CD123⁺ cells is shown. (B) C5aR1 expression on pDCs (CD123⁺ cells) of PBMCs from psoriatic patients and healthy individuals (n = 15/group). Representative FCM analyses of C5aR1⁺CD123⁺ cells are illustrated. Gating strategy is shown in Figure S8. (C) Percentage of C5aR1⁺CD123⁺ cells and MFI of C5aR1 expression on pDCs (CD123⁺ cells). Values are presented as mean ± SEM and data were obtained from at least two independent experiments. ^*p < 0.05; ^***p < 0.001.