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. 2019 Aug 7;10:1814. doi: 10.3389/fmicb.2019.01814

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Copyright © 2019 Liu, Wang, Zhang and Zhu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MafB mRNA and protein expression in chronic hepatitis C patients (n = 29) and healthy individuals (n = 21). MafB mRNA relative level was semi-quantified by real-time PCR. (A) Comparison of MafB mRNA relative level in PBMCs from chronic hepatitis C and healthy individuals. Significances were determined using Student’s t test. (B) Comparison of MafB mRNA relative level in PBMCs from different HCV genotypes. Significances were determined using one-way ANOVA. MafB protein expression was measured by Western blot. (C) Representative Western blot analysis was shown. (D) Comparison of MafB protein expression in PBMCs from chronic hepatitis C and healthy individuals. Significances were determined using Student’s t test. (E) Comparison of MafB protein expression in PBMCs from different HCV genotypes. Significances were determined using one-way ANOVA. (F) Correlation between MafB mRNA relative level and serum IFN-α1 was determined using Spearman correlation analysis. (G) Correlation between MafB protein expression and serum IFN-α1 was determined using Spearman correlation analysis. (H) Correlation between MafB mRNA relative level and serum IFN-β was determined using Spearman correlation analysis. (I) Correlation between MafB protein expression and serum IFN-β was determined using Spearman correlation analysis. Individual level for each enrolled subject was shown.