Figure 1.

Composition and metabolites of commensal, gingivitis, and cariogenic biofilms. (A) Relative abundance of major bacterial genera of the three biofilms is shown. Remaining genera are included in “other”. (B) Lactic acid production, total protease activity (FRET probe: PEK-054) and gingipain protease activity (FRET probe: BikKam15) of biofilms that were cultured from saliva of individual donor (in black) or pooled saliva (in red). The same biofilms were used in this study as previously used in Janus et al. (2015) and Buskermolen et al. (2017).