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. 2019 Aug 7;10:839. doi: 10.3389/fphar.2019.00839

Table 1.

Performance comparison of pharmacogenomic (PGx) relationships obtained from our proposed pipeline with other benchmark datasets (OMIM, CTD, and PharmGKB).

Context type TP TN FP FN Sensitivity Specificity Efficacy Precision Recall F measure Accuracy
Our pipeline with “PharmGKB” 1,509 208 254 78 82.6 86.9 88.2 0.904 0.930 0.923 89.1
Our pipeline with “OMIM” 2,225 79 78.0 77.5 81.8 0.600 0.681 0.764 59.3
Our pipeline with “CTD” 1,776 153 375 70.7 65.5 72.2 0.729 0.803 0.801 79.7
Our pipeline with (“PharmGKB” AND “OMIM” AND “CTD”) 1,875 102 275 75 82.3 84.4 93.3 0.896 0.852 0.828 94.7

PharmGKB corpus compared to that of our pipeline and the articles extracted in these datasets. The formulae used for calculating the accuracy of the proposed pipeline compared to the other datasets (ref. Supplementary Table 5 for detailed analysis).