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. 2019 Aug 13;39(8):BSR20182226. doi: 10.1042/BSR20182226

Figure 6. Inhibition of miR-30b-3p repressed tumorigenesis and metastasis in glioma cells in vivo by up-regulating RECK.

Figure 6

(A) Tumor volume after alteration of miR-30b-3p and RECK; (B) tumor weight after alteration of miR-30b-3p and RECK on the 35th day; (C) tumor size after alteration of miR-30b-3p and RECK on the 35th day; (D) protein expression of the metastasis-associated genes and the extent of AKT phosphorylation after alteration of miR-30b-3p and RECK detected by Western blot analysis; *, P<0.05 compared with the mimic-NC group; #, P<0.05 compared with the inhibitor-NC group; and P<0.05 compared with the RECK NC group; △, P<0.05 compared with the pcDNA3-RECK + miR-30b-3p NC group; n=12; the comparison among multiple groups was analyzed by one-way ANOVA, and comparison of data at different time points was analyzed using repeated measures analysis of variance; the data were expressed using mean ± SEM; Abbreviation: SEM, standard error of the mean.