Figure 1.

H/R injury in IEC‐6 cells and II/R damage in mice. (a, b) Cellular morphology and viabilities of IEC‐6 cells. After hypoxia for 4 hr and reoxygenation for 0, 120, 720, and 1,440 min, the percentages of viable cells were determined using MTT assay (n = 6). (c, d) H&E staining (200× magnification) and histopathological scores (Chiu's score) in mice (n = 8). Scale bar = 100 μm. Male C57BL/6 mice were randomly divided into sham group and II/R groups (45 min of ischaemia and reperfusion for 30, 90, 720, and 1,440 min). All data are expressed as the mean ± SD. *P < .05, significantly different from control groups; ^# P < .05, significantly different from 120 min of reoxygenation or 90 min of reperfusion group