Figure 5.

Quinic acid (QA) promotes glucose‐induced insulin secretion. (a) INS‐1E cells were starved for 1 hr in the absence or presence of QA; thereafter, insulin secretion was measured after 1‐hr incubation in 2.5‐ or 16.7‐mM glucose supplemented or not with QA, at the indicated concentration. (b) INS‐1E cells were treated for 3 days with QA, and then insulin secretion was measured with or without QA as above. (a, b) Insulin secretion was normalized to total protein content. Data shown are individual values with means ± SEM from n = 6 experiments. *P <.05, significantly different as indicated; one‐way ANOVA