Figure 6.
MN‐08 attenuated cerebral vasospasm after SAH in rats. (a) Representative H&E‐stained cross sections of rat basilar arteries after SAH. Scale bars: 20 μm; magnification, ×400. (b–d) Semi‐quantification of the (b) internal perimeter of lumen, (c) cross‐sectional area of internal lumen, and (d) wall thickness of basilar arteries. Data shown are means ± SEM (n = 7 for sham, model, MN‐08 [6 mg·kg−1], memantine (MEM) and nimodipine (NIM) groups; n = 8 for MN‐08 [3 mg·kg−1] and MN‐08 [12 mg·kg−1] groups). # P < .05, significantly different from sham group; *P < .05, significantly different from model group; one‐way ANOVA and Dunnett's multiple comparisons test