Table 3.
Univariate and multivariate analyses regarding distant metastasis for patients in the model development cohort.
| Variables | Univariate analysis | P | Multivariate analysis | P |
|---|---|---|---|---|
| HR (95%CI) | HR (95%CI) | |||
| Age | 0.987 (0.969-1.005) | 0.165 | ||
| Histology | 0.001 | |||
| Scc | 1 | 1 | ||
| Non-Scc | 2.219 (1.366-3.604) | 2.343 (1.438-3.817) | 0.001 | |
| Tumor size (cm) | ||||
| <4 | 1 | 0.013 | ||
| ≥4 | 1.644 (1.097-2.464) | |||
| Parametrial infiltration | ||||
| No | 1 | 0.095 | ||
| Yes | 1.591 (0.923-2.744) | |||
| PLN metastasis | ||||
| No | 1 | 1 | ||
| Unilateral | 1.950 (1.137-3.342) | 0.015 | 1.670 (0.933-2.988) | 0.084 |
| Bilateral | 2.846 (1.859-4.355) | < 0.001 | 2.182 (1.320-2.988) | 0.002 |
| Common iliac LNM | ||||
| No | 1 | < 0.001 | 1 | |
| Yes | 3.728 (2.333-5.956) | 2.200 (1.254-3.861) | 0.006 | |
| Number of positive PLN | ||||
| 0 | 1 | |||
| 1-2 | 1.952 (1.246-3.059) | 0.003 | ||
| ≥3 | 3.690 (2.260-6.025) | < 0.001 | ||
| Diameter of positive PLN (cm) | ||||
| 0 | 1 | |||
| <1.5 | 2.314 (1.477-3.628) | < 0.001 | ||
| ≥1.5 | 2.675 (1.640-4.362) | < 0.001 | ||
| Para-aortic LNM | ||||
| No | 1 | |||
| Yes | 3.509 (2.088-5.897) | < 0.001 |
Abbreviations: Scc = squamous cell carcinoma; PLN = pelvic lymph node; LNM = lymph node metastasis.